201-L36-elecpropnerv-2009ND slides

201-L36-elecpropnerv-2009ND slides - I. Neuronal Tissue Two...

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I. Neuronal Tissue A. Nerve Cells (Neurons) Involved in the generation and interpretation of ‘Electrical Signals’ B. Glial Cells Support neuronal cell activity Two cell types:
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Dendrites Cell Body Axon Synapses collect information process information propagate info transmit info
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“Bioelectricity” Resting Membrane Potential Action Potential
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II. ‘Resting Membrane Potential’ Baseline electrical condition (of ALL cells) Depends on 2 parameters A. Transmembrane Ion Gradients (particularly Na + & K + ) B. Membrane Permeability to those ions
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A - = negatively charged protein and phosphate
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A. Ion Gradients Na,K-ATPase develops and maintains steady-state ion gradients for ALL cells Na + Na + K + K + B. Permeability ATP K + ‘leak’ channels present in ALL cells
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K + K + (+) (-) Channel Cytoplasm Outside
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2 opposing forces Chemical & Electrical 1) Chemical force (K + gradient) Tends to ‘push’ K + out 2) Developed Electrical Force (inside negative) Tends to ‘pull’ K + in
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Na + Na + K + K + ATP (+) (-) ‘K + leak channel’ cyto out
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In a ‘Typical’ cell
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This note was uploaded on 03/24/2010 for the course PSIO 201 taught by Professor Stanescu during the Spring '08 term at Arizona.

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201-L36-elecpropnerv-2009ND slides - I. Neuronal Tissue Two...

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