lecture4_slides

lecture4_slides - Pharm Sci 310 Lecture 4: Pharmacodynamics...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Lecture 4: Pharmacodynamics (drug actions and their receptors) Arash Bashirullah, PhD 5123 Rennebohm Hall contact: [email protected] Pharm Sci 310 (reading: chapter 2 from textbook) Pharmacokinetics : what the body does to drugs Pharmacodynamics : what drugs to the body two aspects of pharmacology… outline of lecture… how do drugs work? – what is a receptor? – ligands and their properties – types of receptors describing the effects of drugs (drug binding kinetics) – drug response curves – drug safety and effectiveness
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 how do drugs do what they do? “the pharmacological, physiological, or behavioral effects induced by a drug follow from their interaction with receptors” what is a receptor? a protein that is on the surface of (or within) a cell that provides the site(s) where biologically active, naturally occurring, endogenous compounds induce their normal biological effects. CELL RECEPTORS receptors as sense organs of the cell… LIGANDS nucleus
Background image of page 2
3 nucleus CELL RECEPTORS receptor-ligand interactions: molecular switch OFF LIGANDS ON nucleus CELL RECEPTORS receptor-ligand interactions:
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/25/2010 for the course PHARM 310 taught by Professor Marker during the Spring '10 term at Wisconsin.

Page1 / 11

lecture4_slides - Pharm Sci 310 Lecture 4: Pharmacodynamics...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online