lecture_9_2010(pp)

lecture_9_2010(pp) - 2/16/10 BENZODIAZEPINES AND RELATED...

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2/16/10 1 BENZODIAZEPINES AND RELATED ANXIOLYTICS February 18, 2010 Paul Marker, Ph.D.
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2/16/10 2
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2/16/10 3 Anxiety Disorders are the most frequent psychological disorders may lead to high levels of medical and psychological comorbidity Major forms of anxiety disorders Generalized anxiety disorder Panic disorder Social anxiety disorder Posttraumatic stress disorder Prevalence and treatment symptoms may affect 30% of the general population only 15-36% of affected individuals are treated
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2/16/10 4 Insomnia types may be acute with sudden onset in people without a history of insomnia may be a chronic problem for some individuals Insomnia symptoms (may have one, some, or all) trouble falling asleep trouble staying asleep sleep not restorative (lack of feeling rested after sleep) considered insomnia if any of the symptoms last >1 month Insomnia causes, prevalence, and treatment causes are multi-factorial including: physical issues like pain or illness response to the use of some drugs response to strenuous exercise in sensitive individuals result of psychological issues poor sleep environment (e.g. noisy) Insomnia affects ~64 million in U.S. each year for both Anxiety and Insomnia a combination of pharmacotherapy and psychological therapy works best
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2/16/10 5 Benzodiazepines Effects on the body Anxiolytic (antianxiety) Sedative Anticonvulsant Amnesic Muscle relaxant Common benzodiazepine drugs Diazepam (Valium®) – long-acting agent Chlordiazepoxide (Librium®) - – long-acting agent Clonazepam (Klonopin®) – intermediate-acting agent Lorazepam (Ativan®) – intermediate-acting agent Triazolam (Halcion®) – short-acting agent Alprazolam (Xanax®) – short-acting agent Which of the following statements is incorrect? Benzodiazepines A. may produce anxiolytic and muscle relaxant properties. B. include the long acting agent diazepam (Valium®). C.
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lecture_9_2010(pp) - 2/16/10 BENZODIAZEPINES AND RELATED...

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