Lecture%205 - Problem Sets Office Hours DR BOULANGERS...

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1 01/23/07 BILD1 - Lecture 5 1 BILD1 The Cell Prof. Lisa M. Boulanger 01/23/07 BILD1 - Lecture 5 2 Problem Sets, Office Hours, Problem Set 2 online NOW! Key posted Saturday Will be discussed in Sections THIS WEEK Problem Set 1 Key online NOW GUEST LECTURE THURSDAY: Dr. Gentry Patrick DR. BOULANGER’S OFFICE HOURS THIS WEEK ONLY : WED 1-3 PM 01/23/07 BILD1 - Lecture 5 3 Review session Midterm 1 Review Session Saturday 1/27 4:30-7:30 Solis 107 01/23/07 BILD1 - Lecture 5 4 EXAM POLICIES For detailed makeup exam and regrade policies, please see class website! All exams are closed book, no notes, own work No dropped exams; Midterms = 25% EACH (2), cumulative final = 50% Photo ID required, no phones, PDAs Exam MUST be taken in non-erasable pen to be considered for a regrade 50% of exams will be photocopied Makeup exams, with valid doctor’s note only, will be oral exam by Professor within one week 01/23/07 BILD1 - Lecture 5 5 MIDTERM 1 DOES INCLUDE TODAY’S LECTURE, BUT DOES NOT INCLUDE THURSDAY’S! Includes: PROBLEM SETS 1 and 2 CHAPTERS 2- 5, 8 & 9 ALL SUPPLIMENTARY READINGS REVIEW SESSION THIS SATURDAY, JAN. 27 th , 4:30-7:30 pm, Solis 107 MIDTERM 1 WILL BE TUESDAY JANUARY 30 th 12:30 – 1:50 IN ***** MANDEVILLE AUDITORIUM!!! ***** MIDTERM 1 01/23/07 BILD1 - Lecture 5 6 MIDTERM 1 Multiple choice, fill in the blank, matching Similar in content to the types of questions on Problem Sets NO SCANTRONS or blue books needed!
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2 01/23/07 BILD1 - Lecture 5 7 Highlights from previous lecture: DNA and RNA are polymers of nucleotides, linked by (covalent) phosphodiester bonds DNA and RNA encode amino acid sequence Lipids are formed of fatty acids and glycerol joined by an ester / glyceride bond Phospholipids result from bonding between a glycerol, two fatty acids, and a phosphate group Amphipathic molecules can form micelles or lipid bilayers, depending on their shape Bilayers can undergo fission (1->2) and fusion (2->1) O CH 2 O O - OP OH O - 01/23/07 BILD1 - Lecture 5 8 Highlights from previous lecture: Catabolism = releasing energy by breaking complex molecules (exergonic) Anabolism = consuming energy to build complex molecules (endergonic) Thermodynamics: 1) energy is conserved. 2) Gibbs free energy ( Δ G) is negative for spontaneous reactions (entropy increases) Enzymes reduce the activation energy (E A ) and speed reactions Enzymes are regulated by pH, temperature, competitive and allosteric inhibitors, allosteric activators, feedback inhibiton, localization, covalent modifications Releases heat (exothermic) G reaction reactants products Δ G - 01/23/07 BILD1 - Lecture 5 9 ATP and energy coupling Glycolysis and cellular respiration (Kreb’s cycle + oxidative phosphorylation) Fermentation THIS LECTURE: 01/23/07 BILD1 - Lecture 5 10 Releases heat (exothermic) G reaction reactants products G reaction reactants products Δ G - Δ G + Anabolism (endergonic) Requires energy Released > consumed spontaneous Consumed > released not spontaneous Catabolism ( exergonic) Releases energy Using released energy to drive anabolic processes 01/23/07
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This note was uploaded on 03/26/2010 for the course BENG 110 taught by Professor Schmid-schoenbein during the Spring '08 term at UCSD.

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Lecture%205 - Problem Sets Office Hours DR BOULANGERS...

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