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Lecture%2010 - Problem Set 4 posted,discussed this week...

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1 02/13/07 BILD1 - Lecture 10 1 BILD1 The Cell Prof. Lisa M. Boulanger 02/13/07 BILD1 - Lecture 10 2 Problem Set 4 posted,discussed this week Today’s lecture: 3 movie links Regrade requests must be submitted in writing, on paper by THIS THURSDAY Whole exam will be regraded Simple addition errors will just be corrected— exam will not be regraded 02/13/07 BILD1 - Lecture 10 3 Cell signaling: local and long distance Local signaling Gap junctions, plasmodesmata (membrane contact) Cell-cell recognition (cell surface molecule contact) Autocrine signaling (to self) Paracrine signaling (to neighbor) Long-distance signaling Hormones Highlights from previous lecture: 02/13/07 BILD1 - Lecture 10 4 Highlights from previous lecture: Three stages of signaling: Reception (conformational changes) G protein coupled receptors Tyrosine kinase receptors Ion channels Intracellular receptors Transduction Phosphorylation Second messengers cAMP G proteins IP 3 , DAG, Ca 2+ Response Transcription factors Specificity, amplification, reversal 02/13/07 BILD1 - Lecture 10 5 THIS LECTURE: MITOSIS 02/13/07 BILD1 - Lecture 10 6 The continuity of life Is based upon the reproduction of cells, or cell division
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