exam_2-08-answers

exam_2-08-answers - Zoo/Psych/Neuro 523 Exam 2- ANSWERS 1...

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Zoo/Psych/Neuro 523 Exam 2- ANSWERS 2008 1 1). (20 points; 5 points each part) Please briefly describe, and comment on the function of: Synaptic vesicle A synaptic vesicle is a small membrane-enclosed organelle that contains packaged neurotransmitter. It is stimulated to release transmitter by exocytosis, which is the fusion of the vesicle membrane with the presynaptic terminal membrane. If you told the synaptosome story (how vesicles were isolated and shown to contain transmitter) you would get credit Arrestin Arrestin is a protein in the cytoplasm of the photoreceptor cell. After light has activated rhodopsin, the C terminal tail of rhodopsin is phosphorylated by rhodopsin kinase. Phosphorylated rhodopsin has a high affinity for arrestin, which occludes the G protein activating site, so no more G-protein can be activated. Essentially the binding of arrestin turns off the light response Gating current Gating current is a component of the capacitative current. It is due to the movement of the S4 transmembrane helix, with its positively charged amino acids, within the membrane. It precedes the opening of the voltage-gated Na channel Pacinian corpuscle The Pacinian corpuscle is a mechanoreceptor in the skin.
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This note was uploaded on 03/26/2010 for the course ZOOLOGY 523 taught by Professor Stretton during the Fall '08 term at Wisconsin.

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exam_2-08-answers - Zoo/Psych/Neuro 523 Exam 2- ANSWERS 1...

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