PROBLEM_SET_1.466n - 4 What is the difference between...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Genetics 466 Fall 2008 Sean Carroll PROBLEM SET #1 (lectures 14-16) You should be familiar with the following terms: Hydrogen bonds Okazaki fragment nucleoside origin of replication nucleotide phosphodiester bond DNA polymerase I Theta structures DNA polymerase II replication fork DNA ligase telomerase 1. In what component parts do RNA and DNA differ? How do their general structures differ? 2. A new organisms has been found and the base composition of its DNA was determined to be 22 percent cytosine. What is the percentage of thymine? guanine? adenine? The uracil content of RNA is found to be 24 percent. Explain. 3. What holds the DNA double helix together? What is an easy way to destroy the double helix structure?
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: 4. What is the difference between conservative and semi-conservative replication? 5. Why does replication proceed from the 5’ to 3’ direction? 6. The rate of DNA replication averages 1000 nucleotides per second. How long does it take E. coli to replicate its 4,000 kb genome if replication is bidirectional from one origin? Unidirectional from one origin? How long would it take to replicate a human chromosome of 150,000 kb if replication is bidirectional from one origin at the centromere and the rate is 3,000 nucleotides per minute? From 1,000 origins? 7. What is meant by discontinuous replication? 8. What are the three physical requirements for DNA polymerase to proceed? 9. What is a primer?...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern