Lectures 2 and 3 Control of the Endocrine system 10

Lectures 2 and 3 Control of the Endocrine system 10 - NPB...

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PB 128 Lectures 2 and 3: Control of the Endocrine System NPB 128 Lectures 2 and 3: Control of the Endocrine System I. General strategies of control II. Life history of hormones A. Synthesis B. Secretion rate C. Transport D. Metabolism III . Anterior pituitary cell types and hormones Posterior pituitary hormones IV. Comparative pituitary morphology V. Hypothalamic releasing/inhibiting hormones
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ense ffector I. General strategies of endocrine control First Order Neuroendocrine Loop Sense organ Effector organ CNS Sense Effector CNS Endocrine OR Second Order Neuroendocrine Loop organ organ Gland Sense rgan Effector rgan CNS Endocrine land 1 Endocrine land 2 Third Order Neuroendocrine Loop organ organ Gland 1 Gland 2 Direct Endocrine Loop Effector organ Endocrine Gland
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II. Life history of hormones A. Synthesis 1. Peptide hormones Hormone gene-hormone mRNA-hormone peptide chain Peptide synthesized on rough ER as pre-pro-peptide Pre sequence- target to secretion vesicles, pro sequence? Often glycosylated on trip through Golgi to secretory vesicles ORMONE RE RO H OOH HORMONE PRE PRO CHO CHO CHO NH 3 + -- COOH
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2. Thyroid hormone synthesis Figure 11-37 Withers Comparative Animal Physiology
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Secreted thyroid hormones (80% from gland) (20% from gland, 0X more active 10X more active than T4)
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3. Steroid hormone biosynthesis romatase 5 dihydrotestosterone 5 Reductase Aromatase
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II. Life history of hormones, continued B. Secretion rate- peptide hormones can be controlled
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This note was uploaded on 03/28/2010 for the course NPB NPB 128 taught by Professor Furlow/chang during the Winter '10 term at UC Davis.

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Lectures 2 and 3 Control of the Endocrine system 10 - NPB...

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