Unformatted text preview: mucous production), leukotrienes (prolonged contractions of smooth muscle) (histamines happen right away and leukotrienes are a delayed response) Hives – fluid filled wheals from skin mast cells – the mast cells are bound with IgE that responds to allergen Hay Fever – upper respiratory mast cell Asthma – lower respiratory mast cells cause constriction of smooth muscles in bronchial tubes Anaphylatic shock – systemic dilation, causing shock. – because all the capillaries are dilated so they become leaky Treatment? – Induce different antibody than IgE – Try to generate an IgG response (mast cells primarily bind to IgE if available) *Figure 18.3*...
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- Fall '09
- Histamine, Mast cell, mast cells, Immune Disorders