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Outline for HIV

Outline for HIV - C hapter29c overstheproble msandc o...

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Chapter 29 covers the problems and complications of HIV in much greater depth than we will be covering.   Please use it as a resource if you want to know more about this serious problem. Acquired immunodeficiency- (Section 29.1)  Need to know Table 25.5 for next class A. HIV- Human Immunodeficiency Virus (Table 29.4)  Over time, HIV has learned to be human   specific – the envelope of the virus comes from humans – the viral spikes are made of gp120 – S tructure (Fig. 29.3)-the main genes to know are gag/pol/env. The major proteins of HIV are   derived from these genes . 1) Genome is two copies of a single stranded RNA molecule.   2) gp120/gp41 surface protein.    this is the most mutational part of the virus (the env gene is   translated into the mRNA that yields the gp120/gp41 surface protein) 3) Reverse transcriptase  – enzyme that synthesizes double-stranded DNA complementary to an   RNA template; target of a number of anti-HIV medications. 4) Integrase  – Enzyme of human immunodeficiency virus that integrates its linear DNA form   into the host chromosome.
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