Lecture%202

Lecture%202 - Carol D’lima Mann Lab 101 12-2 on Wednesday...

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Unformatted text preview: Carol D’lima Mann Lab 101 12-2 on Wednesday Zachary Bent RMI 3215 1/21 RMI South 2211 Tuesday and Thursday 9-11 am Bokyung Lee RMI 3215 1/21 RMI South 2211 Tuesday and Thursday 4-6 pm Email policy Exams Text for the class Wednesday March 3rd Viruses-have genetic material (DNA or RNA) Prions-no genetic material Eukaryotes Organelles True nucleus Protozoa and worms Yeasts and molds Prokaryotes No organelles No internal membrane Viruses<Bacteria<Fungi<Protozoa<Other parasites Bacterial cell: 1-5 μm (1000 to 5000nm) Virus: 20-200 nm Fungi: >30μm Visible to eye= >100μm Resolved by light microscope= 0.2-200μm or larger Thickness of cell membrane = 6nm Water molecule = 0.4nm Gram positive intoxication Gram negative infections gram positive Cell wall much thicker No outer membrane gram negative Thinner cell wall Outer membrane “Enteric family”: Gm negative, facultatively anaerobic rods enteric – of or within the intestine Most are intestinal parasites of animals and/or humans but also grow in food Infections: living cells must be ingested, and their colonization of the body is a prerequisite for disease symptoms. The incubation period is usually a day or two for diseases that stay in the GI tract (may be longer) Specific toxins Enterotoxins: bacterial derived molecules that cause gastroenteritis e.g. cholera toxin Cytotoxins: affect functions of the GI tract but also other sites, cause dysentery and kidney symptoms Endotoxins: Toxin which is part the microbial cell body as opposed to EXOTOXINS Exotoxins are released from the microbial pathogens as free molecules There is one known endotoxin: the lipid part (“lipid A”) of the lipopolysaccharide of gm –ve outer cell membrane...
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Lecture%202 - Carol D’lima Mann Lab 101 12-2 on Wednesday...

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