M3_6 - Unit 6 How do we control chemical change? The...

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Chemistry XXI The central goal of this unit is to help you identify the structural and environmental factors that can be used to control chemical reactions. Unit 6 How do we control chemical change? M4. Selecting the Reactants M2. Changing the Environment . M3. Analyzing the Products Analyzing the effect of charge stability. Exploring the influence of external factors. Evaluating the impact of electronic and steric effects. M1. Characterizing Interactions Recognizing interactions between reacting molecules.
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Chemistry XXI Unit 6 How do we control chemical change? Module 3: Analyzing the Products Central goal: To predict and control the properties of chemical products based on the analysis of charge stability.
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Chemistry XXI Drugs’ Properties Predicting and controlling acid-base properties of drugs is of central importance in drug design. How can we predict or control As we have seen, at a certain pH in our body the relative amount of a drug in its acid or basic form will be determined - HA
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Chemistry XXI Charge Stability To judge the potential strength of an acid or a base we need to analyze the stability of their conjugate pairs. The more stable the conjugate pair, The central problem is then to predict or control the stability of the charge in the conjugate species.
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Chemistry XXI Charge Stability Analyses of charge stability are of central importance in making decisions about chemical reactivity. Factors to consider: What atom is the charge on? How delocalized is the charge? What types of atoms or groups of atoms are nearby? The influence of these factors are commonly called “ electronic effects .”
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Chemistry XXI Factor 1 What atom is the charge on? The most important factor for determining charge
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M3_6 - Unit 6 How do we control chemical change? The...

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