29 Gas Transport2 - hemoglobin: Describe &...

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SI Leader: Anita Vijapura Spring 2010 BSC2011 1/28/10-1/29/10 1 Gas Transport 2 Explain how transport pigments do their job: What does the oxygen dissociation curve tell you? What general conclusion can you make about this curve? Compare the saturation of O 2 for myoglobin and hemoglobin At the O 2 pressure of the lungs: At the O 2 pressure of the tissues: What conclusion can you make about the O 2 transport capabilities of myoglobin versus hemoglobin? If the pressure of O 2 at the tissues falls, which pigment releases more free O 2 ? Except: Define P 50 for a transport pigment: What is the relationship between P 50 and the affinity of the pigment for O2?
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SI Leader: Anita Vijapura Spring 2010 BSC2011 1/28/10-1/29/10 2 Thus, animals that live in hypoxic environments have _________-affinity transport pigments. (_______ P 50 ). Animals that live in hyperoxic environments have __________-affinity transport pigments. (_______ P 50 ). Compare the oxygen affinity for maternal hemoglobin vs. fetal
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Unformatted text preview: hemoglobin: Describe & explain the shape of the O 2 Dissociation Curve for hemoglobin: What is the interaction between the Hemoglobin subunits called? The Bohr Shift explains the effects of a _____________ in pH. As a result, the affinity of hemoglobin for oxygen _______________. What does this mean about the oxygen transport to the tissues? Why is there a change in pH? CO 2 + H 2 O H 2 CO 3 ______ + ______ This reaction uses what enzyme? At the tissues: C O 2 enters the blood cell as ______. It combines with water and forms ________________________________. Hemoglobin, found in the _____________, picks up _______ & ________. Effect? ________ makes its way towards the lungs. At the lungs: C O 2 enters the blood cell as _______. (This causes a chloride shift!) Hemoglobin releases ________ & ________. ________ & ________ combine to form _______ that will exit the blood cell and enter into the lungs....
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This note was uploaded on 03/30/2010 for the course BSC BSC2011 taught by Professor Evans during the Spring '10 term at École Normale Supérieure.

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29 Gas Transport2 - hemoglobin: Describe &...

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