physiology hw 4

physiology hw 4 - remodels itself in response to stress...

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March 18, 2008 Physiology 42-202 Homework #4 1. The process of bone repair involves four stages: Hematoma formation, fibrocartilaginous callous formation, bony callus formation, and bone remodeling. Bone remodeling involves the three stages of Activation, Resporption, and Formation. During the activation phase, the osteoclastic precursors are activated. During the resorption phase, initial resorption by osteoclasts and later resorption by mononuclear cells takes place. During the formation phase, the termination of resorption and invasion of resorption cavities by preosteoblasts, differentiation of preosteoblasts into osteoblasts, and the formation of new bone matrix and subsequent mineralization by osteoblasts takes place. Sources: Lecture notes 2. Because the grandmother has osteoperosis, her bones are weak, and the screw would shatter her weak bones. Also, the placement of a plate would reduce stress on the bone, resulting in weakening of the bone, according to Wolf’s Law which states that the bone
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Unformatted text preview: remodels itself in response to stress. Sources: Lecture notes and review session material 3. 4. (a) The ejection fraction will decrease because since the valve is replaced, there is no more leaking of blood. Therefore, the heart doesn’t have to work as hard to pump a sufficient volume of blood (b) left ventricular systolic pressure would rise because there is no longer a leaking of blood through the mitral valve. 5. Pheochromocytoma causes hyperactivity of the sympathetic nervous system, including increased blood pressure. This tumor results in uncontrolled secretion of epinephrine, and because of this the adrenergic receptors are stimulated excessively. This in effect results in peripheral vasoconstriction and cardiac stimulation. This results in high blood pressure, and therefore hypertension.
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physiology hw 4 - remodels itself in response to stress...

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