020909 Section 05

020909 Section 05 - Patrick Corpuz pcorpuz@ucsd.edu A01:...

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Patrick Corpuz pcorpuz@ucsd.edu A01: Mon. 8-8:50 Center 207 02/09/09 OH: Fri. 8-8:50 Leichtag Lobby A04: Wed. 8-8:50 Center 220 WEEK 5 I. Autonomic Neurotransmitters * Remember the autonomic division of the peripheral nervous system consists of pre-ganglionic neurons that exit the CNS and synapse on the cell bodies of post-ganglionic neurons 1. All preganglionic neurons (in both parasympathetic and sympathetic branches) release Ach onto cholinergic nicotinic receptors 2. The postganglionic neurons of the parasympathetic branch release Ach onto cholinergic muscarinic receptors of the effector 3. The postganglionic neurons of the sympathetic branch release Norepinephrine onto adrenergic receptors 4. Sympathetic i. ganglia are close to synapse, short ii. Preganglionic fibers, secrete Ach at the synapse iii. Postganglionic – contain nAchR 1. Long : stretch to reach organs that they innervate 2. Target is either a gland or a muscle a. Have adrenergic receptors classified into alpha and beta 5. Parasympathetic i. Long coming out of vagus nerve ii. Long preganglionic fibers 1. Secrete Ach onto postganglionic cell iii. Postganglionic synapse close to organ that is innervated 1. Have different receptors , mAchR 6. Adrenal Sympathetic pathway i. Secrete Epi, NE ii. Enters circulation and secreted out of the body iii. Reach cells and stimulate the cells that have adrenergic receptors II. Motor pathways 1. Reflexes i. Stretch reflex (Figure 13.4 - monosynaptic) 1. used to monitor muscle tone and prevent overstretching 2. even at rest, extrafusal fibers maintain a certain level of tension 3. Effect: if muscle is stretched, increase output of sensory signals to spinal cord, increased output through motor neurons, muscle contracts and returns to resting length ii. Knee jerk reflex (Figure 13.7 – polysynaptic) 1. Illustrates the reciprocal inhibiton of the antagonistic muscle 2. Effect: quadriceps contracts, swings lower leg forward; hamstring relaxes, allows extension of leg
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This note was uploaded on 03/31/2010 for the course BIMM bimm 100 taught by Professor Dr.sato during the Winter '08 term at UCSD.

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020909 Section 05 - Patrick Corpuz pcorpuz@ucsd.edu A01:...

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