Week%208%20-%20Teacher%20Edition

Week%208%20-%20Teacher%20Edition - BIPN 100 Dr Fortes...

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BIPN 100 Chris Childers Dr. Fortes Winter 09 Smooth Muscle: Diagram the smooth muscle contraction mechanism starting with the entry of calcium from the extracellular fluid, and ending with increased muscle tension. increase in cytoplasmic Ca2+ levels Ca2+ binds calmodulin Activates CaM kinase phosphorylation of MLCK (Myosin light chain kinase) phosphorylation of myosin allows it to bind actin As with all biological processes it is important to consider not only the activation mechanism, but also the inactivation (“off mechanisms”). Give two examples of “off mechanisms” for smooth muscle contraction. 1. Remove Ca2+ (via 1 Ca2+/ 3 Na+ antiport or Ca2+ ATPase) 2. Hydrolyze myosin light chain (via myosin phosphotase) Cardiac Anatomy: On the following diagram, draw: superior and inferior vena cava, the pulmonary artery, aorta, right and left atria, right and left ventricles, tricupsid and bicuspid (mitral) valves, semi-lunar valves, Cardiac Muscle : Lecture 18 – February 20 th Lecture 19 - February 23 rd Smooth Muscle Contraction Cardiovascular Anatomy Cardiac Muscle Contraction Cardiac Muscle Action Potential Excitation conduction Electrocardiogram
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BIPN 100 Chris Childers Dr. Fortes Winter 09 Diagram the cardiac muscle contraction mechanism starting with an action potential travelling through the sarcolemma and ending with increased muscle tension. Action potential along the membrane goes into the t-tubule
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Week%208%20-%20Teacher%20Edition - BIPN 100 Dr Fortes...

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