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Week 10 Teac - BIPN 100 Dr Fortes Lecture 23 March 6th ADH Natriuretic Peptides RAAS System Hypertension drugs Venous Valves Capillary Exchange

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BIPN 100 Chris Childers Dr. Fortes Winter 09 Natiuretic peptides, as the name implies, have effects on sodium concentrations in the body. One of the most researched peptide is ANP which stands for __ATRIAL NATIURETIC PEPTIDE___ which is secreted upon stimulation of ____STRETCH RECEPTORS IN THE ATRIA________. ANP acts on the ______KIDNEY___________ to cause ______VASODILATION____________ and ______DECREASE SODIUM REABSORPTION_________________. Describe the Renin-Aldosterone-Angiotensin stem, including the appropriate hormones, where they are secreted, and what enzymes catalyze the conversions. Decrease in blood pressure (and sympathetic stimulation) secrete renin which converts angiotensinogen to angiotensin I ACE (Angiotensin converting enzyme) converts angiotensin I to angiotensin II which causes… o Arterial constriction o Increase secretion of aldosterone from the adrenal cortex Increases Na+ reabsorption, K+ excretion, H2O absorption Describes the effects of the following drugs: ACE Inhibitiors anti hypertension meds Beta-1 Blockers decrease sympathetic tone of the heart decrease cardiac output and blood pressure Ca2+ channel blockers (smooth muscle) decreasing vasoconstriction Alpha Blockers – blcok alpha receptors vasodilation (by decreasing vasoconstriction) The flow of fluids into and out of the capillaries is regulated by two processes – filtration and absorption. Filtration is the movement of fluid out of the capillary into the surrounding areas while absorption is the movement of fluid into the capillary. What are the primary driving forces behind each process? What equations define the outward and inward flows of filtration and absorption, respectively? Which of these driving forces change from one end of the capillary to the other? Which are constant? Filtration: outward movement of fluid - What creates the driving force? Hydrostatic pressure differences - What determines the resistance? Numbers and cross sectional area of the pores - Outward Flow = K (P cap – P IF ) Absoprtion: inward movement of fluid
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This note was uploaded on 03/31/2010 for the course BIMM bimm 100 taught by Professor Dr.sato during the Winter '08 term at UCSD.

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Week 10 Teac - BIPN 100 Dr Fortes Lecture 23 March 6th ADH Natriuretic Peptides RAAS System Hypertension drugs Venous Valves Capillary Exchange

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