411pretestkey - MCB 411 Pretest The name of your 181...

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MCB 411 Pretest The name of your 181 instructor(s) and institution: Have you taken Genetics (MCB 320)? The name of your instructor(s) Have you taken any of the following courses: Cell Biology (MCB410) or Biochemistry (MCB 460 or 462) (circle the number if you have taken these) What does the term “central dogma” refer to and why is it important? Originally to the idea of one way flow of information from DNA to mRNA to protein, used by almost all life forms Why does A pair only with T and G only with C in double stranded DNA? Why does G not pair with T? hydrogen bonding and shape/width of purines/pyrimidines The start of the coding region for the human B-globin gene is 5’-ATGGTGCAC-3’. What is the sequence of the complementary strand of this segment of DNA. 3’-taccacgtg-5’ Consider a replicating chromosome. How does DNA polymerase know when it has made a mistake? How does it fix a mistake? (Give details if you can) DNA polymerase requires a paired 3’OH to add another nucleotide; if an
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411pretestkey - MCB 411 Pretest The name of your 181...

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