This preview shows page 1. Sign up to view the full content.
Unformatted text preview: transcription factors and other regulators of gene expression. C) ENDOPLASMIC RETICULUM (ER) i) A lipid bilayer system of tubules, cisternae and vesicles in the cytoplasm of eukaryotic cells; cis-face component is continuous with outer nuclear membrane. ii) Provides a compartment for the synthesis of lipids and sterols and detoxification of xenobiotics (SER) or synthesis of secretory proteins (RER). Site of preliminary processing of these products: e.g., folding, glyscosylation, sorting into transport vesicles. D) MICROTUBULES (MTs) i) 25 nm diameter dynamic tubules composed of alpha and beta tubulin dimers; in the cytoplasm of eukaryotic cells. ii) Major component of cytoskeleton working in conjunction with motor proteins responsible for cell shape stability, transport of intracellular components, arrangement of organelles, and chromosome movement (as the mitotic spindle)....
View Full Document
- Spring '08