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Unformatted text preview: HUMAN SYSTEMIC PHYSIOLOGY NPB 101 Spring 2010 CRN 72879 MTWRF 4:10  ­ 5:00 PM 123 Sciences Lecture Hall Instructors •  Dr. Charles Fuller –  –  –  –  –  –  –  –  –  –  –  –  Office 280H Briggs Hall E ­mail: [email protected] Office hours: MTWR 5:10 ­6:00 PM (during lecture weeks), by Appt.; 197 Briggs Hall Office 191 Briggs Hall E ­mail: [email protected] Office hours: To Be Announced (during lecture weeks), by Appt.; 197 Briggs Hall Office 2041A SLB E ­mail: [email protected] Office hours: To be Announced, by Appt.; 2041A SLB •  Dr. Jack Goldberg •  TA: Kristyn Ringgold Required Textbook •  Human Physiology: from Cells to Systems –  Author, publisher: Sherwood, Thomson/Brooks/Cole –  7th edi]on, 2010 –  Required readings are different because exam ques]ons may be generated directly from required readings, whether or not the material was presented in lecture. –  Recommended readings encompass material relevant to lectures, but (unless covered in class) will not be covered by exam ques]ons. •  Reading assignments will consist of required & recommended readings. •  Copies of the textbook and addi]onal reading material (if any) are on 2 ­hour reserve in Shields Library. PDFs... MP3s... and COURSE WEBSITE •  •  Lectures will be presented as power ­point slides. PDFs of these slides will be posted on the [email protected] website (hdps://smartsite.ucdavis.edu). We will try to podcast all lectures and post MP3 files of these on the [email protected] website. –  We do not recommend relying on these recordings in lieu of aZending and taking notes during lecture. •  •  •  •  Announcements, supplemental slides, topical outlines, readings, etc. will also be made available on the [email protected] website. [email protected] offers several capabili]es that will not be ac]vely u]lized. Please email Instructors via campus email addresses above, rather than via the [email protected] web site. If you do not adend lectures, it remains your responsibility to obtain all informa]on presented in class and on the course website, including announcements, details about exams, and reading assignments. –  For example, Instructors will not be ac]ve Chat Room par]cipants. –  You will need to check [email protected] regularly. Course Schedule •  •  •  •  •  •  •  •  •  Introduc]on (1 lecture) Neurophysiology (13 lectures) Muscle Physiology (3 lectures) MIDTERM1 Cardiovascular Physiology (9 lectures) Respiratory Physiology (5 lectures) Renal Physiology (4 lectures) MIDTERM 2 Gastrointes]nal Physiology (4 lectures) Endocrinology (5 lectures) Reproduc]on (2 lectures) FINAL (Comp) EXAMINATIONS •  All exams will be mul]ple ­choice and machine scored. •  There will be 3 exams  ­ two 50 ­minute midterm exams and a 2 ­hour final exam. –  Midterm I (30 ques]ons; covering lectures 1 ­17 & Required Reading): Thursday, April 22 –  Midterm II (30 ques]ons covering lectures 18 ­35 & Required Reading): Wednesday, May 19 –  Final Exam (60 ques]ons on all lectures 1 ­46 & Required Reading): Wednesday, June 9 10:30 ­12:30 AM EXAMINATIONS •  Exam ques]ons will be derived from lecture and required reading. •  •  Exams are mul]ple choice and machine scored – you will need a SCANTRON 2000 A sample midterm will be posted on the [email protected] website. –  While other informa]on (e.g., Classical Notes or student notes from previous terms) may be available to you, our exams will be scored solely on the basis of what is presented during this quarter in our lectures and in required readings. •  •  •  The final exam will be comprehensive. There will be NO early exams, NO late exams, and NO make ­up exams. All students are required to take the final exam. –  No excep]ons will be allowed. –  However, please be aware that the material on these exams may not represent the informa]on presented in this course in terms of scope, topic emphasis, ques]on design and current instructor authorship. –  If a student misses the final exam, an “incomplete” or an “F” grade may be assigned, depending on scores earned on the other exams, and depending on the reasons and documenta]on that are provided to Dr. Fuller. •  Individuals with documented learning disabili]es who want extra ]me to take exams need to email Dr. Fuller, and provide wriden documenta]on of the disability, at least two (2) weeks prior to the rst midterm. GRADING •  The “average” grade in NPB 101 generally falls in the “C+” range. •  Leder grades will not be assigned to individual midterm scores. •  The class mean and range for each exam will be announced in class and on the [email protected] website. •  If you miss one midterm for an approved reason, your grade will be based on the exams taken. •  There will be NO allowances made if you miss more than one midterm. –  Missing a second midterm for any reason will result in a zero being recorded for the score on the second exam. CORRESPONDENCE •  You are welcome to e ­mail ques]ons and comments to the course instructors and the TA at any]me. –  We will try to answer your messages promptly. –  It is not always possible for us to provide lengthy responses to some ques]ons you may have. –  If your ques]ons require detailed explana]ons, we will recommend that you consult with the instructors or TA during office hours. –  Only “ucdavis.edu” addresses can be included in this list. –  If you are a concurrent student, you can be added to this list by e ­mailing Dr. Fuller. The Registrar’s office provides instructors with the “ucdavis.edu” e ­mail addresses of enrolled students. •  There will be occasions when the instructors send messages to SmartSite. •  It is your responsibility to check your e ­mail regularly for messages, as these may include informa]on pertaining to the content of lectures and exams. You should also maintain enough space in your mailbox to receive messages. Messages sent to the en]re class will also be posted on the course website. Lecture 1 •  Online Handouts: –  Syllabus –  Lec 1 Notes •  Introduc]on: Physiology –  Defini]on –  Levels of organiza]on –  Principles •  Homeostasis •  Regula]on •  Announcements: –  None •  Reading (Recommended): –  Chapter 1 Physiology •  What is it? •  How does it work? –  Func]onal Anatomy –  Uses physical & chemical principles –  Mul]ple levels of organiza]on –  All the ]me (24/7); varies with ]me of day & season –  Normal physiology = Health –  Abnormal physiology = Disease •  When does it work? • Why is it important? Levels of organiza]on •  Chemical  ­ Molecular •  Cellular –  cell is basic unit of life •  •  •  •  Tissue Organ System Organism Fig. 1 ­1, pg. 3 Func]onal Anatomy ENVIRONMENT IN OUT Organ Systems Fig. 1 ­4ab, pg. 6,7 Principles of Physiology •  Homeostasis –  A dynamic steady ­state of the internal environment –  Not everything •  Regula]on –  How we obtain Homeostasis –  Nega]ve (most common) or Posi]ve Feedback Homeostasis Fig. 1 ­6, pg. 10 Homeosta]c Control Systems •  Nega]ve feedback system –  Primary type of homeosta]c control –  Opposes ini]al change –  Components •  Sensor –  Monitors level of a regulated variable regulated •  Integrator (Control Center) –  Compares sensor’s input with a set point •  Effector –  Makes a response to produce a desired effect Regulated Fig. 1 ­8a, pg. 16 Homeosta]c Control Systems •  Posi]ve feedback system –  Amplifies an ini]al change. –  Does not occur as osen as nega]ve feedback system. –  Example: •  Uterine contrac]ons become increasingly stronger un]l the birth of the baby. Where Do we Start? Which system should we study first? •  Most func]ons involve mul]ple systems, and each system is complex. •  So, we should learn individual systems first and then build from there. •  The nervous system controls many major func]ons, and it allows us to: –  Interact with the world. –  Sense and respond to internal and external s]muli, –  Move through and act on our surroundings. •  It uses electrical signals to func]on. •  So... we will begin with the nervous system. –  If we understand those, we can more easily understand other electrical events in other ]ssues (heart, skeletal muscle, smooth muscle, glands). ...
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This note was uploaded on 04/03/2010 for the course NPB 101 taught by Professor Fuller,charles/goldberg,jack during the Spring '08 term at UC Davis.

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