Chem 118A Summary of reactions - Chem 118A Summary of reactions The following list is most of the reactions you should know for the final exam Know this

Chem 118A - Summary of reactions The following list is most of the reactions you should know for the final exam. Know this list well! Success with synthesis problems relies on knowing a) what reagents are used for a particular reaction, and b) what those reagents do to a given starting material/intermediate. 1. Radical halogenation Cl Cl Cl Cl Br Cl 2 light Br 2 light Notes: 1. Radical chlorination gives a mixture of products (remember 1 : 4 : 5 reactivities of primary : secondary : tertiary hydrogen) i.e. it is useless for synthesis because it is very difficult to control what products you want to form! 2. Radical bromination always gives a product where a most highly substituted hydrogen is replaced (remember 1 : 160 : 1700 reactivities of primary : secondary : tertiary hydrogen.) 3. Radical fluorination has even worse selectivity than chlorination (1 : 1.2 : 1.4) i.e. it is just as useless for synthesis as chlorination! 4. Radical iodination occurs too slowly, if at all.