MCB164+MT1+S05+KEY

MCB164+MT1+S05+KEY - Name_KEY MCB164 Spring 2005 Page 1 of...

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Name__________KEY_____________________ MCB164 Spring 2005 Page of 6 ID #________________________________ FIRST MIDTERM April 25, 2005 Question Points Score 1 9 Mean = 56.8+ 11.1 2 14 3 12 High = 33 4 15 Low = 33 5 20 6 30 Total 100 This examination is closed book. There are 6 pages to the exam. Please count them before you start to make sure all are present . Please write your name on each page of the exam . Answer each question in the space provided. If additional space is required use the back of the page and indicate clearly that you continued your answer on the back. Do not attach additional pages. GOOD LUCK! Student authorization: I authorize the instructor to return the graded exam to me in the main office or to distribute it in the bin for me to pick up. Signature _____________________________ Date_____________________ 1
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Name__________KEY_____________________ MCB164 Spring 2005 Page of 6 1. (9 points) Give a hypothetical example that illustrates the following genetic formalism: An informational suppressor is typically allele-specific and gene non-specific in the manner in which it suppresses a mutant phenotype. A nonsense mutation (for example, an amber mutation) in YFG1 (your favorite gene) can be suppressed by a compensatory mutation in a tRNA, allowing the recognition of amber stop codons by an amino acid charged tRNA, thereby bypassing the early translational stop in amber yfg1 alleles. Such an “informational suppressor” would likely be able to suppress an amber mutation (and ONLY an amber mutation) in SUG1 (some uninteresting gene). Informational suppressors are useful for dissecting the genetic code, but will not help in finding other genes that interact with or act in parallel pathways with YFG1 . 2. (14 points) You have just started a internship to study
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This note was uploaded on 04/04/2010 for the course MCB 164 taught by Professor Burgess during the Spring '08 term at UC Davis.

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MCB164+MT1+S05+KEY - Name_KEY MCB164 Spring 2005 Page 1 of...

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