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Unformatted text preview: The two homologs are held together by a much shorter region of sister chromatid cohesion compared to centromere proximal crossover (i.e. bivalent #4) NB: Telomere shortening is generally associated with lagging strand DNA replication. Since there is no DNA replication during the arrest period, telomeres, in principle, should not be getting shorter. 3. Diagram the chromosome segregation pattern in female meiosis leading to an egg disomic for chromosome 21 where the effect is due to a telomere proximal crossover event. 4. How many gametes are formed per meiosis in female mammals? One: The other chromosomes are contained in one of two polar bodies, which are degraded once the zygote forms. mom dad 1 st polar body (no chromosome 21 2nd polar body chromosome 21 disome Ovum chromosome 21 disome...
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- Spring '08