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Unformatted text preview: D. Demethylation of cytosine is required for H3 methylation at K9. E. Demethylation of H3K9 2me is required for cytosine demethylation. 2. (3 points) Cytosine methylation is associated with (active / inactive ) chromatin. (circle one) 3. (4 points) Would you predict that CMT is directly involved in the spreading of heterochromatin into adjacent euchromatin? Explain your answer No: CMT recognizes a different mark than it promotes. That means that there is not a mechanism to propagate the mark by spreading as HP-1 does. HP-1 both recognizes H3K9 2me and recruits a methylase that creates another binding site for HP-1....
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- Spring '08