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MCB164S09+HW1 - Cell 135 261-271 2 Modeling complex genetic...

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MCB164S09 HW #1 50 points Due date: Thursday May 7: draft #1 for peer review (in class). Tuesday May 12: final draft due in class Choose one of the two manuscripts to read. Your assignment is to describe ONE major finding of the paper you choose. Your review should be 2 pages double-spaced. Final submission should be single-spaced. Your review should include: Relevant background information (10 points) State the hypothesis that they test (10 points) Describe methods to address hypothesis (10 points) Results (10 points) Conclusions and future directions; can be author’s or your ideas (10 points) 1. RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination. 2008.
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Unformatted text preview: Cell 135: 261-271 2. Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. 2007. Genes Dev . 21: 148–159. You should be able to access these papers and other like them from the PubMed site. http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed . Keep in mind that access to many of the electronic journals requires that you go through a University server. Articles in Pubmed Central are all free. http://www.pubmedcentral.nih.gov/ . You may discuss the articles with your classmates but your submitted writing should be yours alone....
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