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MCB164S09+Practice+problems409key

MCB164S09+Practice+problems409key - MCB164 S09 Practice...

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MCB164 S09 1 Practice problem 4/09/2009 MCB164 practice problem set #2 April 9, 2009 These problems are taken directly from exams and in class exercises from previous years. Some are from homework problems and these are much harder. Those will be indicated here. Your first homework project will be assigned after first midterm. Another set of practice problems will be posted next week. The first midterm is coming up. Only two more lectures to go. 1. (12 points) Mark each statement about C. elegans as either T (True) or F (False): _ _T ____ Males arise among progeny of a self-fertilizing XX hermaphrodite by one of several possible spontaneous nondisjunction events that can produces nullo-X gametes. ___ F ___ Dominant embryonic lethal mutations can generally be maintained as a stock if a balancer chromosome is present. The only way a dominant lethal could be maintained is if it were conditional. ___ F ___ In the “green eggs and him” screen described in class, the him/him homozygous mutants are always male while him/+ are always hermaphrodite. The homozygous him/him mutants used in the screen are hermaphrodites. The self-fertilize and produce significant numbers of male embryos which can be visualized by expression of the male embryo-specific promoter xol-1p fused to green fluorescent protein (GFP). ___ T ___ Gender in C. elegans is determined by the ratio of the number of X chromosomes to the number of autosomes. Can also state F-gender is determined by the activity of tra-1 2. How many gametes are formed per meiosis in female mammals? One: The other chromosomes are contained in one of two polar bodies, which are degraded once the zygote forms.
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MCB164 S09 2 Practice problem 4/09/2009 3. You have just started a internship to study SGS1 in yeast. Write a 2-3 sentence excerpt from your e-mail to your best friend where you describe your new project using the following words correctly: mutation, allele, mutant, genotype, phenotype, haploid, heterozygote . (Don’t worry about the science, just worry about using the words correctly in a genetic context).
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