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Brett_Genetics PS1

Brett_Genetics PS1 - these mutants to wild type cells and...

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Discussion Section Problem Set 1 1. There are a great number of different ways to distinguish the blood of two individuals. The first is the classic ABO system. The second is two alleles L M and L N that determine the M, N, and MN blood groups. A third way is by looking for the dominant allele R that produces a Rh + phenotype. Individuals homozygous for the recessive allele r have the Rh phenotype. Consider the case that two men are suing for paternity of the same three children. Given the phenotypic information below, can you conclusively determine which man is the father of the children? Husband O M Rh + Wife AB MN Rh Wife’s Lover A N Rh + Child 1 O MN Rh + Child 2 A N Rh + Child 3 A MN Rh 2. A yeast geneticist takes cells that are unable to grow without the presence of Adenine (they have the ade1 mutation), and mutagenizes them. He sees that a small number of the mutants are prototrophic (they have regained the ability to grow without adenine). He crosses
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Unformatted text preview: these mutants to wild type cells and sporulates them to get haploid cells. He notices that his mutants actually fit into two different categories according to their haploid progeny. Describe a model that would explain the differences between these two groups. (1) Prototroph X wild type: all progeny are prototrophic (2) Prototroph X wild type: 75% are prototrophic, 25% require adenine 3. The production in eye color in Drosophila requires the dominant allele A . The dominant allele P of a second independent gene turns the pigment to purple, but its recessive allele leaves it red. A fly producing no pigment has white eyes. Two pure lines were crossed with the following results. Explain the mode of inheritance and show the genotypes of the F 1 and F 2 generation. P red-eyed Female X white eyed Male F 1 purpled-eyed Females and red-eyed Males F 1 X F 1 Both Males and Females: 3/8 purpled-eyed 3/8 red-eyed 2/8 white-eyed...
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