Kim_Week1 - PP

Kim_Week1 - PP - ICE-BREAKER Get into pairs Ask your...

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Unformatted text preview: 1/31/2010 ICE-BREAKER Get into pairs. Ask your partner the following questions… you will be reporting their answers back to the class. MCB 104: Genetics, Genomics & Cell Biology Discussion WEEK 1: MENDELIAN GENETICS Name One advantage of using pea plant One disadvantage of using pea plant One advantage of using Drosophila One disadvantage of using Drosophila TERMS TO KNOW Gene Allele Phenotype vs. genotype Recessive vs. Dominant Homozygous vs. heterozygous Pure line Parental generation (P) First filial generation (F1) Second filial generation (F2) Self vs. cross-pollination (mating types) Stigma vs. anthers TERMS TO KNOW Law of Equal Segregation (Mendel’s 1st Law) Law of Independent Assortment (Mendel’s 2nd Law) Monohybrid cross vs. dihybrid cross Test cross Mutant vs. wild-type Autosomal vs. Sex-linked Sex chromosome Homogametic vs. heterogametic X-linked vs. Y-linked TERMS TO KNOW Chromatid vs. Chromosome Sister chromatids Homologous vs. non-homologous chromosomes Centromere Telomere Karyotype USEFUL STATISTICAL TOOLS Probabilities Product Rule Sum Rule Chi Square Test Χ2 = Σ (O – E)2 / E for all classes 1 1/31/2010 CROSSES & PUNNETT SQUARES P (Pure lines) F1 (monohybrid) F2 YY X yy Yellow Green all Yy Yellow ? MONOHYBRID CROSS Self-pollinate or cross two individuals from F1 of previous example Y Y y y Genotypic Ratio YY : Yy : yy 1:2:1 Phenotypic Ratio Yellow : Green 3 :1 YY Yy yellow yellow Yy yy yellow green CROSSES & PUNNETT SQUARES P (Pure lines) F1 (dihybrid) F2 rrYY X RRyy Round, Yellow Wrinkled, Green all RrYy Wrinkled, Yellow ? DIHYBRID CROSS Self-pollinate or cross two individuals from F1 of previous example Possible gametes RY Ry rY ry DIHYBRID CROSS RY RY Ry rY ry RRYY Round, Yellow Round, Yellow MITOSIS Ry RRYy rY RrYY Yellow Round, Yellow ry RrYy Yellow Round, Yellow Review the following figures: Detailed: Box 2-1 on Pg. 47 Simple: Fig 2-15 on Pgs. 44-45 Yellow Round, Yellow RRYy Yellow Round, Yellow RRyy g reen Round, green RrYy Yellow Round, Yellow Rryy g reen Round, green RrYY Yellow Round, Yellow RrYy Rryy g reen Round, green rrYY rrYy rrYy rryy Yellow Yellow Yellow Round, Yellow Wrinkled, Yellow Wrinkled, Yellow RrYy Yellow Round, Yellow Yellow g reen Wrinkled, Yellow Wrinkled, green Genotypic Ratio 1:1:2:2:4:2:2:1:1 Phenotypic Ratio 9:3:3:1 2 1/31/2010 MEIOSIS Review the following figures: Detailed: Box 2-2 on Pgs. 48-49 Simple: Fig 2-15 on Pgs. 44-45 Questions???? THIS WEEK… Work out a tri-hybrid cross & determine genotypic and phenotypic ratios AaBbCc X AaBbCc Catch up on week 1 Reading: Pgs. 37, 46, 89-103, 61-65 Problems: Chapter 2: #13, 22, 26, 31, 43, 52, 64 Chapter 3: #10, 15, 18 Come to office hours or email with questions Week 2 Reading: Pgs. 129-135, 137-145, 230-239 Problems: Chapter 4: #2, 10, 16, 17 Chapter 6: 2, 5, 64, 66 3 ...
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This note was uploaded on 04/05/2010 for the course MCB 104 taught by Professor Urnov during the Spring '09 term at Berkeley.

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