This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Page 2 LEARNING STRATEGIES CENTER Spring 2010 4. How would you synthesize (N,N-dimethylaminomethyl)cyclohexane from bromocylohexane? The product is an N-substituted amine, which can be formed by reduction of an amide. The amide results from a reaction of an acid chloride with an amine. The acid chloride results from the reaction of SOCl 2 with a carboxylic acid that is formed by carboxylation of the Grignard reagent synthesized from the starting material. Br MgBr O C N(CH 3 ) 2 NaOH (CH 3 ) 2 NH O C Cl SOCl 2 C O OH Mg, ether 1. CO 2 , ether 2. H 3 O Br CH 2 N(CH 3 ) 2 ?...
View Full Document
This note was uploaded on 04/05/2010 for the course CHEM ORGANIC CH taught by Professor Dotsevisogah during the Spring '09 term at Cornell University (Engineering School).
- Spring '09