Lab 8 Cardiovascular System

Lab 8 Cardiovascular System - LAB 8. THE CARDIOVASCULAR...

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LAB 8. THE CARDIOVASCULAR SYSTEM 1 | Page STATION 1. HISTOLOGY OF BLOOD AND BLOOD VESSELS Textbook Readings. Ch 17 Blood p.637-649; Ch 19 Blood Vessels p.695-701.- OBJECTIVES: 1. To identify histological features of arteries, veins and capillaries. 2. To identify the various blood cells and components from their histological sections. 3. To understand the functions of blood and the various types of blood vessels. With your TA, examine the histological slides of the various blood cells/components and blood vessels that comprise our cardiovascular system. Before leaving this station ensure you can recognize the different types of blood vessels and understand their key role in the body. You will also note that there are various slides that show abnormalities in blood. Try to predict what symptoms/health problem might arise in a patient demonstrating these blood abnormalities. Fill in the tables and draw your impression of what you see under the microscope. A. BLOOD VESSELS TYPE CHARACTERISTICS DRAWING FUNCTION Artery Well-defined lumen (rounded) Composed of 3 layers: 1) tunica intima ( connective tissue & smooth muscle); 2) tunica media (thick layer of elastic fibers, smooth muscles, some recticular and collagen fibers); 3) tunica adventia (thin layer of fibroblasts & macrophages). Vein Three layers (intima, media and adventitia) are not well-defined. Veins have thinner tunica media (less smooth muscle) compared to arteries. Adventitia is larger than the media. Do not retain their shape. Floppy/irregular shape lumen
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LAB 8. THE CARDIOVASCULAR SYSTEM 2 | Page TYPE CHARACTERISTICS DRAWING FUNCTION Capillary Capillaries consist of a single layer of endothelial cells and their basement membrane. Capillaries are wide enough to allow the passage of red blood cells, only one cell at a time Site of exchange of metabolites between blood and tissues. B. BLOOD TYPE CHARACTERISTICS DRAWING FUNCTION Erythrocytes (red blood cells) Non-nucleated; Biconcave discs; Filled with hemoglobin 4-5 million RBC per mm 3 of blood in women, men have 5-6 million/mm 3 . High RBC conc=polycythemia Low RBC conc = anemia Abnormal hemoglobin = thalassemias Neutrophil Tiny light staining granules; Multi-lobed nucleus with lobes connected by thin strands of nuclear material. Most numerous WBC. Account for 50-70% of all leukocytes. If the count exceeds this = acute infection; If the count is considerably less = viral infection Eosinophil Bi- lobed nucleus; Contains large granules which are acidophilic and stain pink/red Account for less than 5% of the WBC's. Increased number of cells = parasitic disease
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LAB 8. THE CARDIOVASCULAR SYSTEM 3 | Page TYPE CHARACTERISTICS DRAWING FUNCTION Basophil Basophilic granules are large, stain deep blue/purple, and are so numerous they mask the nucleus. Represent less than 1% of all
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This note was uploaded on 04/06/2010 for the course NS 3410 taught by Professor Obrien/swanson during the Spring '08 term at Cornell.

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Lab 8 Cardiovascular System - LAB 8. THE CARDIOVASCULAR...

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