CH9 - UNIT II. Cell Chapter 9 Cell Communication and...

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1 UNIT II. Cell Chapter 9 Cell Communication and Regulation of the Cell Cycle
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2 Student Learning Outcomes: Compare and contrast the five common methods of cell-to-cell communication. Describe the three major types of cell surface receptors, and give examples of each. Outline the basic mechanism of different types of signal transduction pathways. Name the stages in a eukaryotic cell's life cycle, and briefly describe the events occurring in each phase.
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3 A plasma membrane is essential for a cell It does isolate the cell from its surroundings A cell cannot survive if it cannot sense changes in the extracellular environment and respond to them
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4 Cell communication is the process of cells detecting and responding to signals in the extracellular environment Needed to coordinate cellular activities in a multicellular organism One important reason for cell communication is to promote cell division
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5 Cell communication or cell signaling involves incoming and outgoing signals Signals are agents that influence the properties of cells Signals affect the conformation of a receptor leading to a response in the cell
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6 Why do cells need to respond to signals? 1. Need to respond to a changing environment Adaptation or a cellular response is critical for survival Glucose acts as a signal to yeast cells to increase number of glucose transporters and enzymes allowing efficient uptake and use of glucose
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8 Why do cells need to respond to signals? Cells need to communicate with each other Cell-to-cell communication Darwin and his son investigated phototropism Auxin is a signaling molecule transmitted from cell to cell and inhibited by the light
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9 Signals relayed between cells 1. Direct intercellular signaling Cell junctions allow signaling molecules to pass from one cell to another 2. Contact-dependent signaling Some molecules are bound to the surface of cells and serve as signals to cell coming in contact with them 3. Autocrine signaling Cells secrete signaling molecules that bind to their own cell surface or neighboring cells of the same type
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10 3. Paracrine signaling Signal does not affect cell secreting the signal but does influence cells in close proximity (synaptic signaling) 4. Endocrine signaling Signals (hormones) travel long distances and are usually longer lasting
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12 3 stages of cell signaling 1. Receptor activation Signaling molecule binds to receptor 2. Signal transduction
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This note was uploaded on 04/06/2010 for the course BIO bio 183 taught by Professor Ferzli during the Spring '08 term at N.C. State.

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CH9 - UNIT II. Cell Chapter 9 Cell Communication and...

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