first_exam__07 - PSL 432 First Hourly Exam Feb. 7, 2006...

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PSL 432 First Hourly Exam Feb. 7, 2006 Form A 1 NAME __________________________________ 1. If hematopoietic stem cells were transplanted into a host and it could be shown that descendents of the transplanted stem cells became neurons, that would be an example of A. apoptosis. B. canalization. C. trans-differentiation. D. embryonic stem cell therapy. E. normal hematopoiesis. 2. Which of the following is FALSE of telomeres? A. Their ends are replicated by DNA polymerase. B. They are highly repetitious sequences of DNA base pairs. C. They are found at the ends of chromosomes. D. They determine the life span of somatic cells. E. They shorten as most cells age. 3. Embryonic stem cells differ from adult stem cells in that only embryonic stem cells A. are 'immortal' with respect to cell division. B. can self-renew indefinitely. C. can produce descendents that are differentiated. D. can be safely transplanted directly into a host. E. are derived from cells cultured from a blastocyst. 4. Based on the assigned reading and lecture notes on apoptosis, which of the following correctly pairs a protein molecule with its role in apoptosis? A. Caspase--controls the permeability barrier of mitochondria B. p53--directly degrades proteins during apoptosis C. Fas--receptor protein that inhibits apoptosis when activated D. Bcl-2--protects cells against apoptosis E. ICE-like proteases--involved in necrosis, not apoptosis 5. Which of the following statements is TRUE? A. The majority of cells in the bone marrow are hematopoietic stem cells. B. Stem cells are identified by marker proteins expressed on their surface. C. Red blood cells (erythrocytes) are the only blood cell not derived from hematopoietic stem cells. D. Intestinal stem cells are found in the intestinal villi. E. Hematopoietic stem cells are embryonic stem cells. 6. Which of the following correctly describes the concept of a cancer stem cell? A. A cell capable of unlimited self-renewal and differentiation. B. A tumor cell resistant to cancer chemotherapy. C. A tumor cell capable of producing a new tumor when transplanted. D. A tumor cell with mutations affecting proliferation and apoptosis. E. A normal tissue stem cell with mutations.
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PSL 432 First Hourly Exam Feb. 7, 2006 Form A 2 7. For the production of embryonic stem cells, which of the following correctly describes an advantage of the somatic cell nuclear transfer (SCNT) method compared to the in vitro fertilization method? A.
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This note was uploaded on 04/03/2008 for the course PSL 432 taught by Professor Several during the Spring '08 term at Michigan State University.

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first_exam__07 - PSL 432 First Hourly Exam Feb. 7, 2006...

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