Lecture 5 - Transmission down an axonimpulse reaches...

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Transmission down an axon—impulse reaches synaptic terminals Presynaptic Neuron Postsynaptic Neuron Electrical Synapse Gap Junctions that allow ions to pass directly from cell to cell --Facilitated Diffusion --Some in the brain --“hard-wiring” in the nervous system --More common in invertebrates --Invertebrates—Stereotypic Response --Vertebrates—Plastic Response Chemical Synapse Ligand-gated Ion Channels --“ligand”—something that binds to something else --Synaptic Cleft in between the 2 neurons --Action potential comes down the axon and reaches the synaptic terminal --Initially highest concentration of Ca2+ is outside --Voltage-gated Ca2+ channel opens up and Ca2+ diffuses into synaptic terminal (facilitated diffusion) --Synaptic Vesicles are full of neurotransmitter molecules --Rapid increase in Ca2+ concentration causes the synaptic vesicle to move toward the synaptic cleft and release its contents --Neurotransmitter diffuses quickly through synaptic cleft --Neurotransmitter binds to the ligand-gated channels and opens it
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This note was uploaded on 04/06/2010 for the course BIO 01-119-10 taught by Professor D'arville during the Fall '09 term at Rutgers.

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Lecture 5 - Transmission down an axonimpulse reaches...

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