Lecture 8 - Growth Hormone(Somatotropin Whole Body is...

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Growth Hormone (Somatotropin) Whole Body is Target --Controlled by releasing and release-inhibiting hormones from hypothalamus --Stimulates production of insulin-like growth factors (IGFs) by the live and other cells (cell division, protein, synthesis and bone growth) --Affects metabolism: increases blood levels of glucose and fatty acids Growth Hormone—Disorders --Pituitary Dwarfism—Hyposecretion during growth years --Gigantism—Hypersecretion during growth years --Acromegaly—Hypersecretion in adult Growth Hormones are very effective in Dogs Differ in regulation in IGF1 (insulin-like growth factor 1) --in some species, IGF has an effect on longevity What about BST (bovine somatotropic hormone)? --increases milk production in cows—species specific—does not affect humans --however, treated cows have more infections than other cows Thyroxine (T 4 ) and Triiodothyronine (T 3 ) --Produced by thyroid but controlled by pituitary and hypothalamus --Increases BMR—basal metabolic rate—rate of aerobic respiration in the body --Most body cells are targets --Amino-acid derivatives T4-4 iodines T3-3 iodines --GENE ACTIVATION::Enter cell, receptors inside cell, gene activated
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Thyroid Hormones—Disorders -- Hyperthyroidism —e.g. Graves’ Disease -immune system attacks the thyroid gland
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This note was uploaded on 04/06/2010 for the course BIO 01-119-10 taught by Professor D'arville during the Fall '09 term at Rutgers.

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Lecture 8 - Growth Hormone(Somatotropin Whole Body is...

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