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Unformatted text preview: diverged. 16) cDNAs lack regulatory region information and intron DNA 17) Pseudogenes lack introns, have a poly-A tail and do not have regulatory DNA sequences upstream of the gene. 18) i) Centromeres and telomeres are important for proper function of chromosomal structures. ii) Transposon-derived repeats have given rise to at least 47 different human genes. iii) Certain genes have repeated sequences which lead to mutation when these regions are amplified (i.e. Huntington’s disease). iv) Transposon-derived sequences have reshaped the genome by aiding the formation of chromosomal rearrangements 19a) The predicted amino acid sequence of the protein product can be examined for protein domains or functional units (protein motifs). b) Northern blot analysis to discover in when and in which tissue the gene is transcribed. Also, knocking out a gene and looking for a phenotype....
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This note was uploaded on 04/07/2010 for the course BIO 105 taught by Professor Sullivan during the Summer '08 term at University of California, Santa Cruz.
- Summer '08