Gene structure3

Gene structure3 - Exon 1 Exon 2 Exon 3 Intron 2 Intron 1 TATAAA STOP CCA A T-25-80 Primary Transcript 1 TA TA A T TTGA CA ~-10 ~-35 Bacterial

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MCB121, C. Gasser Overview of Typical Gene Structure (figures are not to scale) Type I (human rRNA gene cluster, one of ~200 in a tandem array) -156 -107 UCE core enzyme binding site 18S 5.8S 28S Terminator Sequence T-rich + 18 bp conserved region -45 +20 +1 Type III ( Xenopus 5SrRNA gene) +64 +50 ICR A Box C Box Terminator Sequence (4 A's in template strand) +1 +80 +90 +120 Type II (hypothetical plant or vertebrate protein-coding gene) Enhancer Poly A Site A A TA A A +1 ATG TGTGTG
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Unformatted text preview: Exon 1 Exon 2 Exon 3 Intron 2 Intron 1 TATAAA STOP CCA A T-25-80 Primary Transcript +1 TA TA A T TTGA CA ~ -10 ~ -35 Bacterial Operon Promoter Operator ? Coding region 1 Coding region 2 RBS RBS ATG ATG STOP STOP Transcription terminator Genes of Higher Eukaryotes mRNA Primary Transcript +1 AUG STOP AAUAAA AAA. ..AAA Processing mRNA Cap meGppp Poly-A coding 1 code 2 coding 3 coding 1 code 2 coding 3...
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This note was uploaded on 04/07/2010 for the course MCB 120L taught by Professor Fairclough during the Spring '08 term at UC Davis.

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