RelativeResourceManager(23) - Genomics transcriptomics...

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Genomics, transcriptomics, proteomics, and metabolomics: Measurement science at its finest Chem 420 December 03, 2008 Professor Ryan C. Bailey
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Problem set #5 z Posted on Compass z Due in class on Monday, December 8 z Assignments are due at beginning of class—starts at 12 Noon! z For full credit assignments must be in box when the lecture begins. z Any assignment turned in between noon and 12:05 PM will automatically be deducted 5 points. z Assignments will NOT be accepted for credit after 12:05 PM. z Score = 0
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Final Exam Information z Review session: Wednesday, December 10 during class z Exam date, time, and location: Wednesday, December 17, 1:30-4:30 PM z Last names beginning A-Mc : 160 English Building z Last names beginning Me-Z : 217 Noyes Lab z Students will sit every other seat filling room from back z Exam begins promptly at 1:30 PM and ends at 4:30 PM. z Special situations need to notify me in advance to find solution. z Remember, you get one sheet of paper to write anything
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Omics: Where does this term come from? z The suffix “ -om- ” originated as a back-formation from “genome”, a word formed in analogy with “chromosome”. The word “chromosome” comes from the Greek stems “ χρωμ ( ατ )-” ( colour ) and “ σωμ ( ατ )-” ( body ). Because “genome” refers to the complete genetic makeup of an organism, some people have made the inference that there exists some root, *“ -ome- ”, of Greek origin referring to wholeness or to completion , but such root is unknown to most or all scholars. z Because of the success of large-scale genome sequencing, the suffix " -om- " has been picked up by a wide array of other large- scale quantitative biology fields. http://en.wikipedia.org/wiki/-omics
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‘Omic this and ‘omic that z The genome refers to the complete DNA complement of an organism; with its associated field genomics . z The transcriptome , the mRNA complement of an entire organism, tissue type, or cell; with its associated field transcriptomics . z The proteome , the protein complement of an entire organism, tissue type, or cell; with its associated field proteomics. z The metabolome , the totality of metabolites in an organism; with its associated field metabolomics. z The metallome , the totality of metal and metalloid species; with its associated field z The lipidome , the totality of lipids; with its associated field lipidomics. z The glycome , the totality of glycans, carbohydrate structures of an organism, a cell or tissue type; with its associated field glycomics z The interactome , the totality of the molecular interactions in an organism ; a once proposed field of interactomics has generally become known as systems biology z The spliceome (see spliceosome), the totality of the alternative splicing protein isoforms; with its associated field spliceomics . z
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RelativeResourceManager(23) - Genomics transcriptomics...

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