RelativeResourceManager(19)

RelativeResourceManager(19) - Note: z I dont want to...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Note: z I dont want to introduce too much new material today, but want to finish up the last couple slides from last week and also spend time talking about cutting edge applications of mass spectrometry being utilized here at UIUC. z Please take a moment to read the abstract of the primary literature papers we will discuss in class z Papers attached at the end of this pdf. Mass spectrometry: Part 3 Chem 420 November 10, 2008 Professor Ryan C. Bailey Review session and test logistics z Review session: Tonight, 6-8 PM, 161 Noyes Lab z Exam date, time, and location: Wednesday, November 12, 12-12:50 PM z Last names beginning A-Mc : 192 Lincoln Hall z Last names beginning Me-Z : 217 Noyes Lab z NOTE: This is reversed from Exam #1! z Students will sit every other seat filling room from back z Exam begins promptly at 12 noon and ends at 12:50 PM. z Special situations need to notify me in advance to find solution. z Remember, you get one sheet of paper to write anything Brief comments on ICP-MS as a tool for atomic composition analysis z One of the most widely used techniques for elemental analysis z Low detection limits for many elements, high selectivity, and good precision and accuracy. z Quadrupole mass analyzers are often used z Large mass range not necessary for atomic analyses z Compared to optical spectra, ICP-MS data is often easier to interpret z Interferences come from isobaric, polyatomic (adducts), and doubly charged ions. z Matrix effects are an issue and underscore the need for internal standards z Valuable for both qualitative and quantitative analysis. z Detection limits down at ~0.02-0.1 ppb for most elements Applications of molecular mass spectrometry z Versatile detection technology z Not only detects, but provides additional detail in the detection process. z Qualitative and quantitative applications z Identification of compounds and determination of purity z Hyphenated techniques z GC/MS, LC/MS, CE/MS, GC/MS/MS, LC/MS/MS, and LC/MS n Secondary ion mass spectrometry (SIMS) z Useful for determining both atomic and molecular composition of solid surfaces z Surface is bombarded with a high energy beam of ions and the sample is sputtered into the gas phase z Ions generated by electron impact z Ar + (typically, also Cs + , N 2 + , O 2 + , C 60 + , etc.) at 5-20 keV accelerating voltage z Sample sputtered as neutrals and ions z Ions accelerated into mass spec for analysis z Ion beams can be as large as 5 mm or as small as 200 nm in diameter (ion microprobe) z All mass analyzers and ion transducers can work for SIMS z SIMS is a destructive imaging technique that can provide both spatial (microprobe) and depth profiling of atomic and molecular composition Abstract for: Phase Separation of Lipid Membranes Analyzed with High- Resolution Secondary Ion Mass Spectrometry Kraft, M.L., Weber, P.K., Longo, M.L., Hutcheon, I.D., Boxer, S.G....
View Full Document

Page1 / 20

RelativeResourceManager(19) - Note: z I dont want to...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online