Bio416K Osmolarity and Tonicity Practice Problems Spring 2010

Bio416K Osmolarity and Tonicity Practice Problems Spring 2010

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Bio416K Osmolarity and Tonicity Practice Problems Spring 2010 Problem 1 - Using the initial conditions listed below, answer the following questions about water and solute distributions. A patient has the following measured volumes of distribution in the body: Total Body Water = 44 liters Extracellular fluid (ECF) volume = 13.5 liters Plasma volume = 2.8 liters Total body osmolarity is 290 mOsM 1. What is the patient’s intracellular fluid (ICF) volume? 2. What is their interstitial fluid volume? 3. Since their body osmolarity is 290 mOsM, what is the osmolarity of their ICF and ECF? 4. How many osmoles of solute are in their ICF? 5. What is the osmolarity of water (assume it is distilled water)? 6. Pure water is therefore ( hyposmotic, isosmotic or hyperosmotic) to the body. 7. What will the osmolarity of their body be after they drink 500 ml of distilled water? 8. Since there were no osmoles in the water, the number of osmoles in the ECF and ICF has not changed. But the volumes have changed. What is the new volume of water in
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Bio416K Osmolarity and Tonicity Practice Problems Spring 2010

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