Lecture 10 - Electrical Signals in Neurons Bio416K Spring 2010

Lecture 10 - Electrical Signals in Neurons Bio416K Spring 2010

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Structure of a Typical Neuron Target cell Soma Soma
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Trigger zone Graded potential – Point of origin Graded Potentials Target Dendrites or Cell Body Graded potentials Action potentials
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Trigger zone Graded potential – Point of origin Graded Potentials Target Dendrites or Cell Body Graded potentials Action potentials Threshold = - 55 mV
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Structure of a Chemical Synapse Neuronal synapse – pre- and postganglionic neurons Neuromuscular – somatic motor neuron and skeletal muscle Acetylcholine (ACh) ACh nicotinic receptor (ICR - monovalent cation channel)
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Graded Potentials Lose Strength As They Move Through Cytoplasm Lose strength because: 1. Current leak 2. Cytoplasmic resistance
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Subthreshold and Suprathreshold Graded Potentials in Cells
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Spatial Summation of Graded Potentials ACh Na +
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Axon Hillock Acts as an Integration Center Na + Cl - GABA ACh
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Action Potentials Represent Movement of Na + and K + Across Membrane (Fig. 8-9, p. 262)
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Positive Feedback Loop of Votage-gated Na + Channels
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Voltage-gated Na + Channels in the Neuron with Two Gates
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Action Potential Refractory Periods
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Lecture 10 - Electrical Signals in Neurons Bio416K Spring 2010

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