CH 17 - Chapter 17 Cytoskeleton Ropelike fibers Provide...

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1 Chapter 17 Cytoskeleton Ropelike fibers Provide mechanical strength to cells Rigid, hollow cylinders Mitotic spindles, cell polarity, intracellular transport Thin, 2-stranded helix Cell motility, contraction
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2 17_04_protein_ropes_part1.jpg Intermediate Filaments Subunit structure and filament assembly 17_04_protein_ropes_part2.jpg Intermediate Filaments The assembled filament has high tensile strength, which can be further stabilized by cross-linking accessory proteins
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3 Intermediate Filaments Protect cells subject to mechanical stress: Skin and muscle cells Nerve cell axons (long and fragile) Not found in bacteria
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4 17_10_tubes_tubulin.jpg Microtubules Structural polarity 13 parallel protofilaments per microtubule Subunit structure and assembly Microtubules Formed from specialized organizing centers - centrosome Require a nucleation site (starting point) Growth by addition of subunits to the plus end
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5 Microtubules Microtubules have dynamic instability (Grow/shrink) Microtubules Assembly and disassembly occurs only at the ends
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This note was uploaded on 04/09/2010 for the course BIOL 213 taught by Professor Mcknight during the Spring '07 term at Texas A&M.

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CH 17 - Chapter 17 Cytoskeleton Ropelike fibers Provide...

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