CH 18 - 11/30/09 Chapter 18 Cell-cycle control and cell...

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11/30/09 1 Chapter 18 Cell-cycle control and cell death 18_01_cell_cycle.jpg How are these fundamental processes coordinated?
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11/30/09 2 18_02_four_phases.jpg Phases of the eukaryotic cell cycle Interphase = M phase to next M phase S = synthesis G = Gap (cell growth in terms of mass and volume) 18_04_Feedback.jpg Internal and external conditions are monitored in G 1 and G 2 to ensure that the cell is prepared to pass through key steps of the cell cycle (Checkpoints) and that these steps occur in the appropriate sequence
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11/30/09 3 18_09_MPF_discover.jpg
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11/30/09 4 Progression through the cell cycle is controlled by cyclically activated protein kinases Key proteins that initiate or regulate processes such as DNA replication, mitosis and cytokinesis are activated and inactivated by protein kinases Cyclin-dependent protein kinases (phosphorylation/dephosphorylation switches) Cdk’s are present throughout the cell cycle but activated only at appropriate times by binding to cyclins . Timing of Cdk activation is controlled by the
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This note was uploaded on 04/09/2010 for the course BIOL 213 taught by Professor Mcknight during the Spring '07 term at Texas A&M.

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CH 18 - 11/30/09 Chapter 18 Cell-cycle control and cell...

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