Central nervous tissue synapses

Central nervous tissue synapses - bind to the receptor and...

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Central synapses Neural Transmitters o Excitatory CNS neurotransmitters- glutamate and aspartate o Inhibitory CNS neurotransmitters- GABA and glycine Neuropeptides o Neuropeptides Few act as main transmitters Most act as cotransmitters and modulators of the main neurotransmitters Substance-P and B-endorphin o Neuromodulators Help regulate the effectiveness of synapses by changing their excitability levels and rapidity of functional responses Many work as hormones elsewhere in the body E.g. oxytocin, TRH, gastrin, secretin, angiotensin Synapse o Fast- rapid relay of signals occur between the synapse. The neurotransmitter would be able to
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Unformatted text preview: bind to the receptor and open the pores in ion channel Suited for relay o Slow- serve in functions requiring alteration in synaptic properties A neurotransmitter acts as a neuromodulator, binds to membrane receptor that is not an ion channel. The binding allows the activation of adjacent regulatory G-protein, which activates an effector protein Suited for integration of responses Arousal, attention, neural plasticity What happens to a muscle if we increase the frequency of stimulation of the muscle?...
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This note was uploaded on 04/09/2010 for the course MCB 240 taught by Professor Meisami during the Spring '08 term at University of Illinois, Urbana Champaign.

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