Lecture 10 - NPB113 Integration of Cardiac & Vascular...

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1 January 24, 2010 NPB113 Integration of Cardiac & Vascular Function – Reflex Regulation Blood Pressure 10-1 Review of What Determines Pressure Pressure function of Capacitance or Compliance of a Vessel or System & Volume contained within the holding capacity. Arterial System pressure function of volume since capacitance changes minimally. Venous System pressure function of both capacitance and volume since both regulated. Therefore, arterial pressure determined by steady state arterial volume. Arterial volume determined by flow in and flow out. Flow in function of stroke volume (contractility and venous return) and heart rate . Flow out function of heart rate and arteriolar resistance . Since Cardiovascular System a Closed System, both Cardiac Function (Venous Pressure on Stroke Volume & Cardiac Output) & Vascular Function( Cardiac Output on Venous Pressure) Relationships must be satisfied.
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January 24, 2010 NPB113 Integration of Cardiac & Vascular Function – Reflex Regulation Blood Pressure 10-2 Review Components in Baroreceptor Reflex Regulation of Blood Pressure (Discuss Volume Reflex with Renal Physiology) Sensors Baroreceptor Reflex Carotid Sinuses & (Aortic Arch) baroreceptors Afferents baroreceptors receptors Carotid sinus nerves from Carotid Sinuses Central Integration for baroreceptor reflex – cardiovascular areas in medulla Afferent input activates parasympathetic neurons & inhibits activity sympathetic neurons. Efferent activity Baroreceptor Reflex
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Lecture 10 - NPB113 Integration of Cardiac & Vascular...

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