Lecture 8 - NPB113 Vascular System 8-1 Microcirculation and...

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1 January 24, 2010 NPB113 Vascular System 8-1 Microcirculation and Venules and Small Veins Microcirculation – arterioles, capillary network, & initial small venules Arterioles Capillary beds and initial small venules Classification of Capillaries using junctions between endothelial cells – 3 types 1. Capillaries with only with Clefts – very tight junctions between adjacent endothelial cells. Very impermeable Form blood-brain barrier. 2. Discontinuous Capillaries – clefts + channels and spaces within tight junctions. More permeable than capillaries clefts only Found in skeletal muscle, heart, skin 3. Fenestrated Capillaries – large spaces (20 – 200 microns) between adjacent endothelial cells. Very permeable Found liver, spleen, gut. Note – exchange across capillary walls can also occur using transient Vesicular Channels – fusion of intracellular vesicles within membrane forming channel across cell.
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2 January 24, 2010 NPB113 Vascular 8-2 Components and Pressures in Microcirculation
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This note was uploaded on 04/09/2010 for the course NPB npb 113 taught by Professor Goldberg during the Spring '10 term at UC Davis.

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Lecture 8 - NPB113 Vascular System 8-1 Microcirculation and...

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