{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

lecture 3 - DNA Replication an overview 1 Last Time DNA is...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
DNA Replication an overview 1
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Last Time DNA is the genetic material Components Forces holding strands together (3) Higher order structure 2
Background image of page 2
DNA Replication an overview General features of DNA replication: DNA is replicated semi-conservatively The origin of replication is non-random Replication is bi-directional Mechanics of replication DNA polymerases synthesize DNA Leading and Lagging strands, initiated by a primer DNA ligases join strands 3
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Overview General features of DNA replication Basic mechanics of replication http://www.itg.uiuc.edu/technology/atlas/structures/nucleus_actin/images/nucleus_actin.jpg homepage.mac.com/enognog/cell%20cycle.jpg 4
Background image of page 4
How is DNA replicated? 5
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Fig. 20.1 Three hypothetical models 1. 2. 3. 6
Background image of page 6
Matthew Meselson Franklin Stahl Classic experiment to distinguish between 3 replication models 1958 “the most beautiful experiment in biology” 7
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Conservative H H H H L L Expected results HH LL shift Dispersive H H mixed mixed all mixed Expected results L H L H shift Figure 20.3 H L H H L H Semi- conservative Expected results L H H L L L L L L H second generation shift LL L H 8
Background image of page 8
DNA replication is semi-conservative first generation H L H H L H Semi- conservative Expected results HH L H H L L L L L L H second generation shift LL L H 9
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Does DNA replication begin at the same site in every replication cycle?
Background image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 42

lecture 3 - DNA Replication an overview 1 Last Time DNA is...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online