albumin and hypertension final presentation

albumin and hypertension final presentation - The Effects...

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Click to edit Master subtitle style 4/11/10 Heart & Lung Team Jackie Bakalarski, Shauna Collins, Jordan Gales BMS H220.02 The Effects of Albumin on the Development of Essential
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4/11/10 Research Objective Determine effects of albumin on development of essential hypertension Examine albumin as a possible early indicator of essential hypertension development Identify levels of albumin excretion that indicate essential hypertension in patient
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4/11/10 Clinical Importance Human Serum Albumin is the most abundant protein in the blood plasma, comprising nearly half of the blood plasma protein. Maintains oncotic pressure, a type of osmotic pressure exhibited by plasma proteins that pulls water into the circulatory system. Transports thyroid hormones, various fat soluble hormones, fatty acids, unconjugated bilirubin, and many drugs. Multiple studies have shown a strong correlation between urinary albumin excretion levels and health issues such as hypertension, cardiovascular disease and kidney damage. Spangler et al. 1997
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4/11/10 Clinical Importance Continued… 90% of all individuals with hypertension have essential hypertension. Essential hypertension can be defined as elevated blood pressure arising from no known cause. An estimated 73 million Americans are hypertensive. Including two million teens and children. Over half of all Americans age 65 and older have hypertension. Elevated high blood pressure can put excess strain on organs and lead to organ damage, heart attack, stroke, aneurysm, and renal failure. Izzo et al. 2008
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4/11/10 Clinical Importance Continued… The prevalence of hypertension increases with age and hypertension is more common in men than women regardless of age.
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