NewMidterm09Key (1)

NewMidterm09Key (1) - Name Midterm BIMM 134 Spring 2009 1....

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Name Midterm BIMM 134 Spring 2009 1. Rous discovered that: A. Chicken cancers are caused by viruses B. All cancers come from cells C. Black bile tastes bad D. Cell free isolates can cause cancer E. A, B, and D 2. Roentgen’s discovery quickly demonstrated that A. Radiation can cause cancer B. Cells typically become metastatic after malignancy C. Sarcomas and carcinomas arise in different ways D. Differentiation is part of cancer progression E. C and D 3. An adenocarcinoma is A. A cancer arising in myocytes B. A cancer arising in secretory epithelium C. A metastatic cancer of unknown origin D. A benign tumor of the skin E. A type of common brain tumor 1
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Name Midterm BIMM 134 Spring 2009 4. Encapsulation of tumors is A. A sign of late stage malignancy B. Often found in metastatic tumors C. Often found in sarcomas D. A hallmark of benign tumors E. Part of the definition of neoplasia 5. Anaplasia is A. The name of Tsar Nicholas II’s wife B. Part of the process of vascular cooption C. Often correlated with increased cell growth rates D. A factor in EPO regulation during hypoxia E. None of the above 6. Most cancers arise in A. Endothelial tissue B. Mesenchymal tissue C. Epithelial tissue D. Melanocytes E. Tobacco smokers 7. A liver cancer is always a(n) A. Hepatoma B. Hepatocellular carcinoma C. Adenoma D. Hemangioma E. None of the above 2
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Name Midterm BIMM 134 Spring 2009 8. Tumors are monoclonal, and therefore cannot be genetically heterogeneous A. True B. False C. Neither true or false, depends on tumor type D. True for X-linked tumors in females E. True in males but not in females 9. Anchorage independence is A. Typically found in foci of transformed fibroblasts B. A way to determine whether a tumor is from an anchored tissue type C. A measurement of isozyme secretion D. A characteristic of 3T3 cells E. None of the above 10. Nude mice are often used in xenograft studies because A. Their lack of hair leads to low body temperature which is better for growing tumors B. Their lack of hair makes observation of metastasis easier C. Their lack of an innate immune system makes them less likely to reject tumors D. Their defective thymus makes them less likely to reject tumors E. B and C 11. An indirect carcinogen is A. A carcinogen that first causes cancer in one part of the body, and then causes it in a second site B. A carcinogen that makes an existing cancer worse C. A non-carcinogenic substance prior to modification by the body D. A carcinogen that acts to induce anchorage independence but not focus formation E. Both A and B 3
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Name Midterm BIMM 134 Spring 2009 12. The most commonly mutated oncogenes encode growth factors A. True B. False C. True in pediatric cancer but not cancer in adults D. True in mice but not in humans E. None of the above 13. Leukemia patients often suffer from anemia at late stages of the disease, and this is due to A. Liver dysfunction due to liver blockage B. Bone marrow occlusion C. Angiogenesis-related loss of EPO D.
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This note was uploaded on 04/12/2010 for the course BIO BIMM 134 taught by Professor Johnson during the Spring '10 term at UCSD.

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NewMidterm09Key (1) - Name Midterm BIMM 134 Spring 2009 1....

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