DQ5 - allow transport through the NPC 2 How does Ran...

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Discussion question set 5 Chapter 12: Intracellular Compartments and Protein Sorting Nuclear Transport 1a) What is the function of the nuclear pore complex (NPC)? b) What is the basic measure allowing molecules to freely transverse the NPC? c) For molecules that lie outside this measure, what additional factors do you need to
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Unformatted text preview: allow transport through the NPC? 2) How does Ran function in the transport of proteins in and out of the nucleus? What is the localization of its GEF and GAP? 3) Describe an experiment that demonstrates that molecules below a certain size can freely diffuse into the nucleus....
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