Chapter 25 - Microbial Diseases of the Digestive System...

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Unformatted text preview: Microbial Diseases of the Digestive System Chapter 25 Normal Microbial Flora of the Digestive System Mouth 1 ml saliva = millions of bacteria Stomach and small intestine Few organisms due to HCl and rapid movement of food Large intestine 100 billion bacteria per gram of feces 40 % of fecal mass is microbial cell material Lactobacillus, Bacteriodes, Enterobacter, E. coli. Proteus spp. Bacterial Diseases of Lower G.I. Infections Pathogens enters G.I. Tract and multiples Bacteria may penetrate the intestinal mucosa or may pass to other systemic organs Delay in appearance of symptoms while pathogen increases in number or invades tissue Usually a fever Intoxications Ingestion of a preformed toxin Sudden onset of symptoms ( few hours ) Fever not always present Bacterial Diseases of Lower G.I. Diarrhea infections and intoxications Blood or mucus - dysentery Abdominal cramps, nausea and vomiting Defense mechanism to rid body of harmful material Gastroenteritis Inflammation of stomach or intestinal mucosa Campylobacter Gastroenteritis Campylobacter jejuni Gram (-), microaerophilic spiral Most common cause of food borne illness in the U.S. Found in the intestines of many animals, especially poultry Almost all retail chicken is contaminated 60 % of cattle is contaminated 2 million cases per year Escherichia Gastroenteritis 1. ETEC - e nterot oxigenic E . c oli Not invasive Enterotoxin watery diarrhea 2. EIEC - e nteroi nvasive E . c oli Invades intestinal wall Inflammation, fever & Shigella-like dysentery 3. EHEC - 3....
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Chapter 25 - Microbial Diseases of the Digestive System...

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